CJC-1295, Ipamorelin 10mg (Blend)

Description

Ipamorelin and CJC-1295 are both classified as growth hormone secretagogues (GHSs), compounds that stimulate the release of growth hormone (GH), though they differ in structure and pharmacokinetics. Ipamorelin is a synthetic pentapeptide that primarily acts on the growth hormone secretagogue receptor (GHS-R1a) in the hypothalamus and pituitary, selectively promoting GH release without significantly affecting other pituitary hormones like prolactin. CJC-1295, a 29-amino-acid peptide, is a modified analog of GHRH (1–29) designed to mimic natural GH-releasing hormone and enhance pituitary GH secretion.

Overview

Both peptides stimulate the anterior pituitary, promoting natural, pulsatile GH release and subsequent increases in IGF-1, which mediates many of GH’s anabolic and metabolic effects.

CJC-1295 is a tetrasubstituted GHRH 1–29 peptide with four amino acid modifications at positions 2, 8, 15, and 27. These substitutions improve resistance to enzymatic degradation and allow partial binding to plasma proteins such as albumin, extending its half-life from approximately 10 minutes to 30 minutes. When equipped with a Drug Affinity Complex (DAC), CJC-1295 can remain in plasma for over 72 hours, while retaining strong affinity for GHRH receptors.

Ipamorelin is highly selective for GHS-R1a receptors and can trigger GH release rapidly, typically within the first two hours of administration. Unlike other GHSs, it has minimal impact on other pituitary hormones, making it a targeted GH stimulator.

When used in combination—often called a peptide stack—Ipamorelin provides the initial GH stimulation, while CJC-1295 maintains sustained GH release, producing complementary and prolonged effects on the GH–IGF-1 axis.

Reference

https://pubmed.ncbi.nlm.nih.gov/?term=CJC-1295+%26+Ipamorelin

• • • • • • • • • • • • • • •  PLEASE READ • • • • • • • • • • • • • • •

RESEARCH USE ONLY DISCLAIMER AND LIMITATION OF LIABILITY

All articles, materials, content, and product-related information made available on this website are provided strictly for informational and educational purposes only and shall not be construed as medical, pharmaceutical, clinical, or therapeutic advice, nor as a representation of safety or efficacy for any human or animal use.

These products are not drugs, pharmaceuticals, biologics, medical devices, dietary supplements, food products, or cosmetics, and they have not been evaluated, approved, or authorized by the United States Food and Drug Administration (FDA) or any other regulatory authority for human or animal use.

The Company reserves all rights and expressly disclaims any liability arising from misuse, improper handling, or unauthorized application of its products.