BAC Water 5ml

Description

Bacteriostatic Water is a sterile, pharmaceutical-grade solution specifically formulated to inhibit bacterial growth, containing 0.9% benzyl alcohol as an antimicrobial preservative. This carefully prepared solution is ideal for the reconstitution of peptides, proteins, or other laboratory-grade compounds, helping to maintain their stability and extend the usable life of reconstituted preparations.

Each 3 mL vial is manufactured under strict quality controls to ensure consistency, sterility, and reliability for research applications. The inclusion of benzyl alcohol not only prevents bacterial contamination but also helps preserve the integrity of sensitive compounds during handling and storage. This product is intended exclusively for laboratory and research use, providing a safe, dependable solution for analytical workflows, method development, and experimental protocols that require sterile, bacteriostatic conditions.

Whether for peptide reconstitution, dilution of laboratory reagents, or other controlled in vitro studies, our Bacteriostatic Water offers a high-quality, reliable option to support precise experimental work while minimizing contamination risks.

Overview

Bacteriostatic water for injection (bWFI) is a common diluent for parenteral pharmaceutical products. bWFI is sterile water for injection containing one or more suitable antimicrobial agents to suppress the growth of microbial contaminants. United States Pharmacopeia (USP) monograph describes bWFI with pH ranging from pH 4.5 to 7.0. Lacking buffering reagents, bWFI has very low ionic strength, no buffering capacity and is prone to sample contamination. These characteristics pose a challenge for accurate bWFI pH measurements which are characterized by long response times and noisy signals, resulting in inconsistent results. The challenging nature of bWFI pH measurement, however, is not fully recognized as pH is generally considered a routine analytical technique. Even with the addition of KCl to increase ionic strength as recommended by the USP bWFI monograph, variability in pH results is still observed without careful consideration of other critical measurement factors. To bring awareness to the challenges associated with bWFI pH measurement, we present a comprehensive characterization of the bWFI pH measurement process that includes an evaluation of probe suitability, measurement stabilization time, and pH meter settings. While these factors may be non-critical and sometimes overlooked when developing pH methods for buffered samples, they can have a significant impact on bWFI pH measurement. We present recommendations that can help reliable bWFI pH measurements for routine execution in a controlled environment. These recommendations also apply to other pharmaceutical solutions or water samples with low ionic strength.

Reference

https://pubmed.ncbi.nlm.nih.gov/?term=Bacteriostatic+Water

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